WHAT is the product about:
Paracetamol + Propyphenazone + Caffeine (Saridon) is an analgesic or pain killer indicated for1:
- Fast (Starts to release in five minutes)
- Relief of pains such as headache, body pain,dysmenorrhea and toothache
- Relief of pain and fever associated with colds and flu
Reference:
- N Boitel et al. An Open Pilot Study on the onset of action of a propyphenazone/paracetamol/caffeine combination on pain following dental surgery. European Journal of Clinical Research; 8:211-218
- Paracetamol + Propyphenazone + Caffeine (Saridon®) Product Information (PH)
Each Paracetamol + Propyphenazone + Caffeine (Saridon) tablet contains the following active ingredients:
- Paracetamol 250 mg
- Propyphenazone 150 mg
- Caffeine 50 mg
Reference:
- Paracetamol + Propyphenazone + Caffeine (Saridon) Product Information (PH)
It is a mix of Paracetamol, Propyphenazone plus Caffeine. In an analysis of eight studies involving 500 patients with moderate to severe dental pain, Paracetamol + Propyphenazone + Caffeine (Saridon®) was shown to have a fast onset of action (Works in as fast as 15 minutes for pain1 ) and better than the plain analgesics such as paracetamol 500mg, ibuprofen 200mg, aspirin 500mg or placebo2
In conclusion, the data support, that a single dose of Paracetamol + Propyphenazone + Caffeine (Saridon®) is as least as efficacious as Aspirin, Ibuprofen and Paracetamol for the short term treatment of acute pain3
Reference:
- N Boitel et al. An Open Pilot Study on the onset of action of a propyphenazone/paracetamol/caffeine combination on pain following dental surgery. European Journal of Clinical Research; 8:211-218
- Kiersch T, Minic M. The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis). Curr Med Res Op. 2002; 18:1
- Petersen, Birte. 2007. PROPYPHENAZONE+PARACETAMOL+CAFFEINE (SARIDON®) CLINICAL OVERVIEW. Bayer Consumer Care
Paracetamol + Propyphenazone + Caffeine (Saridon) is to be taken in single doses1.
- Adults may take 1-2 tablets
- For Adolescents aged 12-16 years they may take 1 tablet
- If necessary, up to three single doses may be taken within 24 hours. The tablets should be taken with ample water or other fluids. Paracetamol + Propyphenazone + Caffeine (Saridon) should not be taken for more than one week or at doses higher than those recommended, except as directed by a doctor
Reference:
- Paracetamol + Propyphenazone + Caffeine (Saridon) Product Information (PH)
Paracetamol + Propyphenazone + Caffeine (Saridon) should not be taken if there is a history of allergy to the drug or to any component of Paracetamol + Propyphenazone + Caffeine (Saridon). The use of Paracetamol + Propyphenazone + Caffeine (Saridon) should also be avoided or be under direct supervision of your doctor if you have pre-existing medical conditions that increase the risk of unwanted side effects1’2
Please read full product insert for contraindications and list of precautions
Reference:
- Kiersch T, Minic M. The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis). Curr Med Res Op. 2002; 18:1
- Paracetamol + Propyphenazone + Caffeine (Saridon®) Product Information (PH)
Headaches are generally classified by cause:
1. Primary headaches1
A primary headache is caused by overactivity of or problems with pain-sensitive structures in your head.
A primary headache isn't a symptom of an underlying disease.
The most common primary headaches are:
- Tension headache
- Cluster headache
- Migraine
2. Secondary headaches1
A secondary headache is a symptom of an underlying pathology/ disease that can activate the pain-sensitive nerves of the head.
- Acute sinusitis (sinus infection)- Sinus headaches
- Brain tumor
- Dental problems
- Ear infection (middle ear)
- Encephalitis (brain inflammation)
- High blood pressure (hypertension)
- Influenza (flu) and other febrile (fever) illnesses
- Meningitis
Reference:
Whenever the muscles, tissues or blood vessels swell, they stimulate the surrounding nerves or put pressure on them → These nerves in turn send a rush of pain messages to the brain, and this brings on a headache. Inflammatory agents- especially Cox 1/ Cox 2/ Prostaglandins cause the tissues, blood vessels to swell → stimulating the surrounding nerves → which in turn send electrical signals to the pain receptors in the brain1
Reference:
Kiersch et al., 2002 compared the efficacy of Paracetamol + Propyphenazone + Caffeine (Saridon®) with Paracetamol 500 mg, Aspirin 500 mg, Ibuprofen 200 mg alone or placebo in a pooled statistical analysis of eight studies in patients with moderate to severe acute dentoalveolar pain for six hours. Majority of the patients treated with Paracetamol + Propyphenazone + Caffeine (Saridon®) reported significant pain relief and/or no pain compared to the other groups after 30 and 60 minutes of the treatment. Majority of the patients treated with Paracetamol + Propyphenazone + Caffeine (Saridon®) reported no pain or reduction in the intensity of pain with a significant pain relief score as compared to the group administered with individual drugs after four hours of study1
Another pilot study conducted on 20 adults’ outpatients showed that 89% of patients considered Paracetamol + Propyphenazone + Caffeine (Saridon®) as a functional product for dental pain relief with significant onset of action in 15 minutes (p value of < 0.001.)
These studies support Paracetamol + Propyphenazone + Caffeine (Saridon®) as having better analgesic or pain relieving effect vs plain analgesics such as paracetamol 500mg, ibuprofen 200mg, aspirin 500mg or placebo and fast onset of action (Works in as fast as 15 minutes)2,3
Reference:
- Kiersch T, Minic M. The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis). Curr Med Res Op. 2002; 18:1
- Paracetamol + Propyphenazone + Caffeine (Saridon®) Claims Workshop
- N Boitel et al. An Open Pilot Study on the onset of action of a propyphenazone/paracetamol/caffeine combination on pain following dental surgery. European Journal of Clinical Research; 8:211-218
HOW does the product work:
WHO can take this product:
If symptoms persist, consult your doctor.
ASC B043P020421SS
B165N051821SS, B166N051821SS, B123N051921SS, B169N051821SS, B170N051821SS, B171N051821SS, B125N051921SS, B126N051921SS, B153P042121SS